Aniline produced by nitrobenzene hydrogenation contains reaction water together with low-boiling impurities such as benzene, cyclohexylamine and cyclohexanone and high-boiling contaminants such as phenol, diphenylamine and other aromatic compounds. Industrial purification therefore uses separate dewatering/light-boiler and high-boiler separation duties, often under reduced pressure. Structured packing can provide high stage density with low pressure drop, but packing grade, bed arrangement, side draws and liquid distribution should be selected according to the specific impurity being removed rather than bulk aniline purity alone.

Methanol carbonylation produces crude acetic acid containing water, methyl iodide, methyl acetate and trace carbonyl and heavy impurities. The purification train must remove these contaminants while recovering valuable iodide promoter and recycle components. Structured packing can be used in drying, finishing and selected trace-impurity columns because its high stage density and low pressure drop can reduce tower size, improve separation and support energy-integrated revamps. Packing selection must nevertheless follow the exact impurity target, recycle duty, corrosion environment and fouling risk of each column section.

Structured packing can be used in ethylene oxide purification columns to separate EO from water, formaldehyde, acetaldehyde and heavier glycol-related compounds. Its low pressure drop and low liquid holdup are especially valuable because reduced temperature and residence time can help limit unwanted EO-to-glycol side reactions. Packing selection should consider effective stage density, feed and side-draw locations, water distribution, EO recovery, aldehyde specifications and project-specific safety and cleanliness requirements rather than nominal surface area alone.

Cumene-process phenol purification requires a series of fractionation steps because the cleavage stream contains acetone, phenol, cumene, alpha-methylstyrene, acetophenone and heavier byproducts. Structured packing can be valuable in vacuum and high-purity phenol sections because it provides high separation efficiency with relatively low pressure drop and liquid holdup. Packing selection should nevertheless consider the exact column duty, heavy-end contamination, AMS-derived resin formation, liquid redistribution and whether the controlling impurity can actually be removed by distillation.

Nitric acid and water form an azeotrope near 68 wt% HNO₃, so ordinary rectification cannot directly produce 98–99% nitric acid simply by adding more packing. Industrial high-concentration nitric acid plants use processes such as sulfuric-acid extractive rectification or magnesium-nitrate dehydration to overcome this limitation. Structured packing can be used in concentration, acid-water recovery and related sections, but selection must account for severe corrosion, dehydrating-agent circulation, pressure drop, NOx handling and the material compatibility of the complete internals system.